Investigation of air plasma generated by surface microdischarge for decellularized porcine aortic valve leaflets modification,Plasma Processes and Polymers

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Investigation of air plasma generated by surface microdischarge for decellularized porcine aortic valve leaflets modification
Plasma Processes and Polymers ( IF 2.9 ) Pub Date : 2020-07-06 , DOI: 10.1002/ppap.202000100
Chen Lu ₁ , Jinchi Dai ₂ , Nianguo Dong ₂ , Yu Zhu , Zilan Xiong ₁

Affiliation

In this study, the surface microdischarge (SMD) device was used to modify the mechanical properties of decellularized porcine aortic valve leaflets (DPAVL). It was found that SMD treatment under NO_x mode considerably improved the ultimate tensile strength and the Young's modulus of DPAVL, whereas treatment under O₃ mode had no effect. The absorbance band peak at ~1,375 cm⁻¹, measured by Fourier‐transform infrared spectrometer, increased with treatment time in the freeze‐dried DPAVL group under NO_x mode treatment. The microstructure was not destroyed and blood compatibility test showed no toxicity. The reaction between plasma‐activated species and the DPAVL and the pH change, other than temperature/UV irradiation, plays a major role. All of the results indicate that cold atmospheric plasma treatment seems to be a potential alternative for DPAVL modification.

中文翻译：

表面微放电产生的空气血浆用于去细胞猪主动脉瓣小叶修饰的研究

在这项研究中，表面微放电（SMD）装置用于修改去细胞猪主动脉瓣小叶（DPAVL）的机械性能。发现在NO _x模式下的SMD处理显着改善了DPAVL的极限拉伸强度和杨氏模量，而在O ₃模式下的处理没有效果。傅里叶变换红外光谱仪测得的〜1,375 cm ^-1处的吸收带峰随NO _x的冷冻干燥DPAVL组中处理时间的增加而增加。模式处理。微观结构未破坏，血液相容性试验未显示毒性。血浆激活物质与DPAVL之间的反应以及pH变化（温度/紫外线辐射除外）起着重要作用。所有结果表明，冷大气等离子体处理似乎是DPAVL改性的潜在替代方法。

更新日期：2020-07-06

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