Nanoparticles (NPs) which are innovation and research focus in drug delivery systems, still have some disadvantages limiting its application in clinical use, such as short circulation time, recognition and clearance by reticuloendothelial system (RES) and passive targeting in certain organs. However, the recent combination of natural components and nanotechnology has offered new solutions to address these problems. A novel biomimetic platform consisting of nanoparticle core and membrane shell, such as cell membrane, exosome or vesicle vastly improves properties of nanoparticles. These coated nanoparticles can replicate the unique functions of the membrane, such as prolonged blood circulation, active targeting capability and enhanced internalization. In this review, we focus on the newest development of biological-camouflaged nanoparticles and mainly introduce its application related to cancer therapy and toll-like receptor.

作为药物输送系统中的创新和研究重点的纳米颗粒（NPs）仍然存在一些缺点，限制了其在临床中的应用，例如循环时间短，网状内皮系统（RES）的识别和清除以及某些器官的被动靶向。但是，自然成分和纳米技术的最新结合为解决这些问题提供了新的解决方案。由纳米颗粒核和膜壳（例如细胞膜，外来体或囊泡）组成的新型仿生平台极大地改善了纳米颗粒的性能。这些涂覆的纳米颗粒可以复制膜的独特功能，例如延长的血液循环，主动的靶向能力和增强的内在化。在这篇评论中