Abstract

In this article, the effect of surgical damage to the nasal mucosa in rats under the action of general anesthesia was investigated. The motor activity and heart rate variability (HRV) of rats were studied before and 2 days after the surgery. After surgical exposure, motor activity decreased, the time of fading and grooming increased, VLF increased, and HF decreased. Surgical trauma of the nasal septum in rats at the early postoperative stage promotes a pronounced stress response in the form of a sharp shift in the balance of the autonomic nervous system towards the sympathetic level and causes a decrease in exploratory activity, an anxiety, and a depressive-like state in rats.

中文翻译：

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鼻腔手术创伤对大鼠开放视野和自主神经系统行为的影响。

摘要

本文研究了在全身麻醉作用下大鼠鼻黏膜手术损伤的作用。在手术前和手术后两天对大鼠的运动活动和心率变异性（HRV）进行了研究。手术暴露后，运动活动减少，褪色和修饰时间增加，VLF增加，HF减少。大鼠鼻中隔的手术创伤在术后早期以明显的形式促进了明显的应激反应，其中自主神经系统的平衡朝着交感神经水平急剧转移，并导致探索活动减少，焦虑和情绪低落。大鼠处于抑郁样状态。