Pneumolysin, a pore‐forming toxin, is an important virulence factor of Streptococcus pneumoniae with multiple biological activity, such as cell lysis and DNA damage. Thus, targeting this toxin is alternative strategy for the treatment of S. pneumoniae infection.

中文翻译：

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Betulin可减轻肺炎球菌溶血素诱导的细胞损伤和DNA损伤

肺炎链球菌溶血素是一种成孔毒素，是肺炎链球菌的重要毒力因子，具有多种生物学活性，例如细胞裂解和DNA损伤。因此，靶向这种毒素是治疗肺炎链球菌感染的替代策略。