CIRM tools and technologies: Breaking bottlenecks to the development of stem cell therapies.,STEM CELLS Translational Medicine

当前位置： X-MOL 学术 › Stem Cells Transl. Med. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

CIRM tools and technologies: Breaking bottlenecks to the development of stem cell therapies.
STEM CELLS Translational Medicine ( IF 5.4 ) Pub Date : 2020-07-03 , DOI: 10.1002/sctm.20-0055
Lila R Collins ₁ , Kelly A Shepard ₁

Affiliation

The California Institute for Regenerative Medicine (CIRM) has a mission to accelerate stem cell treatments to patients with unmet medical needs. This perspective describes successful examples of work funded by CIRM's New Cell Lines and Tools and Technologies Initiatives, which were developed to address bottlenecks to stem cell research and translation. The tools developed through these programs evolved from more discovery‐oriented technologies, such as disease models, differentiation processes, and assays, to more translation focused tools, including scalable good manufacturing processes, animal models, and tools for clinical cell delivery. These tools are available to the research community and many are facilitating translation of regenerative therapeutics today.

中文翻译：

CIRM 工具和技术：打破干细胞疗法发展的瓶颈。

加州再生医学研究所 (CIRM) 的使命是加快对医疗需求未得到满足的患者的干细胞治疗。这个观点描述了由 CIRM 的新细胞系和工具和技术计划资助的工作的成功例子，这些计划旨在解决干细胞研究和翻译的瓶颈。通过这些项目开发的工具从更多以发现为导向的技术（如疾病模型、分化过程和检测）演变为更多以翻译为重点的工具，包括可扩展的良好制造过程、动物模型和临床细胞交付工具。这些工具可供研究界使用，其中许多工具正在促进当今再生疗法的转化。

更新日期：2020-07-03

点击分享查看原文

点击收藏

公开下载

阅读更多本刊最新论文本刊介绍/投稿指南11