Accelerating CEST MRI in the mouse brain at 9.4 T by exploiting sparsity in the Z-spectrum domain.,NMR in Biomedicine

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Accelerating CEST MRI in the mouse brain at 9.4 T by exploiting sparsity in the Z-spectrum domain.
NMR in Biomedicine ( IF 2.7 ) Pub Date : 2020-07-03 , DOI: 10.1002/nbm.4360
Grzegorz Kwiatkowski ₁ , Sebastian Kozerke ₁

Affiliation

Chemical exchange saturation transfer (CEST) is an MR contrast modality offering an enhanced sensitivity for the detection of dilute metabolites with exchangeable protons. Quantitative analysis requires the acquisition of a number of images (usually between 20 and 50 RF offsets) per Z‐spectrum, leading to long acquisition times of the order of 5‐40 min in practice. In this work, we explore the possibility of employing sparsity in the Z‐spectrum domain (irradiation offset dimension) to provide an accelerated acquisition scheme without compromising the quality of reconstructed CEST spectra.

中文翻译：

通过利用 Z 谱域中的稀疏性以 9.4 T 加速小鼠大脑中的 CEST MRI。

化学交换饱和转移 (CEST) 是一种 MR 对比模式，可提高检测具有可交换质子的稀释代谢物的灵敏度。定量分析需要每个Z谱采集大量图像（通常在 20 到 50 个 RF 偏移之间），导致在实践中采集时间长达 5-40 分钟。在这项工作中，我们探索了在Z光谱域（辐照偏移维度）中采用稀疏性以提供加速采集方案而不影响重建 CEST 光谱质量的可能性。

更新日期：2020-08-04

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