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MOF Histone Acetyltransferase in Blood Cell Development.
Trends in Genetics ( IF 13.6 ) Pub Date : 2020-07-03 , DOI: 10.1016/j.tig.2020.06.010
Yasmin Serina Secanechia 1 , Christophe Lancrin 1
Affiliation  

Gene expression is regulated by transcription factors (TFs) and chromatin modifiers such as histone acetyltransferases (HATs). Pessoa Rodrigues et al. revealed the role of the Males absent on the first (MOF) HAT in hematopoietic stem cell (HSC) differentiation into red blood cells. This work raises interesting questions about how MOF controls other hematopoietic differentiation processes.



中文翻译:

MOF 组蛋白乙酰转移酶在血细胞发育中的作用。

基因表达受转录因子 (TF) 和染色质修饰剂如组蛋白乙酰转移酶 (HAT) 的调节。佩索阿罗德里格斯等人。揭示了第一个 (MOF) HAT 上缺失的雄性在造血干细胞 (HSC) 分化为红细胞中的作用。这项工作提出了关于 MOF 如何控制其他造血分化过程的有趣问题。

更新日期:2020-08-10
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