OBJECTIVE The objective of this study was to determine the internal reliability and construct validity of the Multiple Sclerosis Resiliency Scale (MSRS) in comparison with a common measure of global resilience. METHODS Participants were 216 community-dwelling adults with MS (mean age: 48.8 ± 12.5 years; 77% female; median disease duration: 8 years) recruited through a university-affiliated MS Center. Participants completed the MSRS, 10-item Connor Davidson Resilience Scale (CDRS), Perceived Stress Scale (PSS), and depressive and anxious symptom items from the SymptoMScreen. RESULTS The MSRS exhibited fair to excellent internal consistency (αs 0.74 to 0.91) and divergent validity with disability severity (r = -0.19), MS duration (r = 0.07), and MS subtype (r = -0.01). The MSRS total and Emotional and Cognitive Strategies subscale scores were moderately correlated with the CDRS (rs = 0.50 and 0.62), PSS (rs = -0.56 and - 0.62), depressive symptoms (rs = -0.49 and - 0.54), and anxious symptoms (rs = -0.38 and - 0.047). The MSRS total and Emotional and Cognitive Strategies subscale scores exhibited fair to good accuracy (AUCs = 0.73 to 0.83) for identifying participants in the highest and lowest CDRS quartiles; however, cutoff scores yielded only fair sensitivity and specificity, and the measures differed significantly in classification of participants into highest and lowest quartiles. CONCLUSION Although the MSRS may be useful in assessing resilience to MS-specific challenges, use of a global resilience measure may still be indicated depending on the clinical and research context.

中文翻译：

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多发性硬化症弹性量表 (MSRS) 的信度和效度

目的 本研究的目的是确定多发性硬化症复原力量表 (MSRS) 与全球复原力的通用衡量标准的内部信度和结构效度。方法 参与者是通过大学附属 MS 中心招募的 216 名社区居民 MS 成人（平均年龄：48.8 ± 12.5 岁；77% 为女性；中位病程：8 年）。参与者完成了 MSRS、10 项康纳戴维森韧性量表 (CDRS)、感知压力量表 (PSS) 以及来自 SymptoMScreen 的抑郁和焦虑症状项目。结果 MSRS 表现出相当到极好的内部一致性（αs 0.74 至 0.91）和不同的有效性与残疾严重程度（r = -0.19）、MS 持续时间（r = 0.07）和 MS 亚型（r = -0.01）。MSRS 总分和情绪和认知策略分量表得分与 CDRS（rs = 0.50 和 0.62）、PSS（rs = -0.56 和 - 0.62）、抑郁症状（rs = -0.49 和 - 0.54）和焦虑症状中度相关（rs = -0.38 和 - 0.047）。MSRS 总分和情绪和认知策略分量表分数在识别最高和最低 CDRS 四分位数的参与者方面表现出公平到良好的准确性（AUC = 0.73 至 0.83）；然而，截止分数仅产生公平的敏感性和特异性，并且在将参与者分为最高四分位数和最低四分位数方面的措施有显着差异。结论 尽管 MSRS 可能有助于评估对 MS 特定挑战的适应力，但仍可能需要根据临床和研究背景使用全球适应力测量。