Antarctic krill oil (AKO) is an emerging dietary supplement containing metal ions that influence oil oxidation. Thus, this study focuses on the effect and mechanism of metal ions on phospholipid oxidation in AKO. Firstly, AKO containing Mg²⁺, Mn²⁺, Cu²⁺, Fe²⁺ and Fe³⁺ (200 μmol/kg) were prepared separately and incubated at 60 °C for 6 days. Peroxide value (POV) and malondialdehyde (MDA) content showed that Fe³⁺ exhibited the most effective prooxidative activity, with the prooxidative activity of Fe₂(SO₄)₃ (water-soluble) being stronger than that of ferric oleate (FeOl, fat-soluble). In addition, phosphatidylethanolamine (PE) oxidation degree (more than 90%) was considerably greater than phosphatidylcholine (PC) oxidation degree (about 15%) in AKO. Differences in the structure of head group hindered chelation of PC with metal ions than PE due to electrostatic repulsion and steric hindrance. Therefore, PC significantly inhibited, while PE promoted, the oxidation of polyunsaturated triacylglycerol (TAG), like fish oil (p < 0.01).

南极磷虾油（AKO）是一种新兴的膳食补充剂，其中含有影响油氧化的金属离子。因此，本研究的重点是金属离子对AKO中磷脂氧化的作用及其机理。首先，分别制备含有Mg 2 ⁺，Mn 2 ⁺，Cu 2 ⁺，Fe ²⁺和Fe ³⁺（200μmol/ kg）的AKO ，并在60°C下孵育6天。过氧化物值（POV）和丙二醛（MDA）含量表明，Fe ³⁺具有最有效的前氧化活性，而Fe ₂（SO ₄）₃的前氧化活性（水溶性）比油酸铁（FeOl，脂溶性）强。此外，磷脂酰乙醇胺（PE）的氧化度（大于90％）大大高于AKO中的磷脂酰胆碱（PC）的氧化度（约15％）。由于静电排斥和空间位阻，头部基团结构的差异阻碍了PC与金属离子的螯合，而不是PE。因此，PC可以显着抑制而PE可以促进鱼油等多不饱和三酰基甘油（TAG）的氧化（p  <0.01）。