当前位置: X-MOL 学术Curr. Appl. Phys. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Cancer targeting potential of bioinspired chain like magnetite (Fe3O4) nanostructures
Current Applied Physics ( IF 2.4 ) Pub Date : 2020-08-01 , DOI: 10.1016/j.cap.2020.06.013
S. Swathi , Fuad Ameen , G. Ravi , R. Yuvakkumar , S.I. Hong , Dhayalan Velauthapillai , Muneera D.F. AlKahtani , M. Thambidurai , Cuong Dang

Abstract Iron is significant, earth abundant and inexpensive materials in everyday use. Non toxicity and clean manufacturing process is still a challenging role in scientific world. The chain like Fe3O4 nanostructures were synthesized using the mixtures such as iron nitrate and Rambutan. Magnetite Fe3O4 was verified using X-ray powder diffraction (XRD). Metal oxide (Fe–O) and A1g and Eg phonon modes are substantiated employing Fourier-transform infrared spectroscopy (FTIR) and Raman spectra. A product chemical state was investigated by high resolution X-ray photoelectron spectroscopy (XPS) spectra. Chain like morphology and polycrystalline nature is attributed by transmission electron microscopy (TEM) analysis. Weight loss activity was revealed through thermogravimetric analysis (TGA) analysis. In application studies, higher concentration of Fe3O4 nanostructures was more effective than the low concentration. Moreover, cytotoxicity effects and cell viability on human cancer cell lines were observed and tested for cancer treatment.

中文翻译:

仿生链状磁铁矿 (Fe3O4) 纳米结构的癌症靶向潜力

摘要 铁是日常使用中重要的、地球丰富且价格低廉的材料。无毒和清洁的制造过程在科学界仍然是一个具有挑战性的角色。使用硝酸铁和红毛丹等混合物合成链状Fe3O4纳米结构。使用 X 射线粉末衍射 (XRD) 验证了磁铁矿 Fe3O4。金属氧化物 (Fe-O) 和 A1g 和 Eg 声子模式通过傅里叶变换红外光谱 (FTIR) 和拉曼光谱得到证实。通过高分辨率 X 射线光电子能谱 (XPS) 光谱研究产品化学状态。链状形态和多晶性质归因于透射电子显微镜 (TEM) 分析。通过热重分析(TGA)分析揭示减重活性。在应用研究中,较高浓度的 Fe3O4 纳米结构比低浓度更有效。此外,观察并测试了对人类癌细胞系的细胞毒性作用和细胞活力以用于癌症治疗。
更新日期:2020-08-01
down
wechat
bug