This review summarizes the main strategies aimed at the total synthesis of vincamine and congeners. Then, our contribution in this field is presented: we describe (+)-vincamine semi-synthesis using tabersonine as starting material. Characterization and quantification of the main impurities are discussed, and HPLC conditions, structural elucidation and NMR data of four of them are reported.

中文翻译：

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长春胺的合成和半合成

这篇综述总结了针对长春胺和同类物的全合成的主要策略。然后，介绍了我们在该领域的贡献：我们描述了以塔布草碱为原料的（+）-长春胺半合成。讨论了主要杂质的表征和定量，并报道了其中四种杂质的HPLC条件，结构鉴定和NMR数据。