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An improved abdominal phantom for intrafraction image guidance validation
Physics in Medicine & Biology ( IF 3.5 ) Pub Date : 2020-07-02 , DOI: 10.1088/1361-6560/ab9456
Charles K Matrosic 1, 2 , Bryan Bednarz 1 , Wesley Culberson 1
Affiliation  

A dynamically compressible phantom of the human abdomen that simulates organ motion with breathing is being developed for possible testing of image-gated beam delivery in radiotherapy. The polyvinyl chloride plastisol (PVCP) phantom features a cavity that can contain a deformable normoxic polyacrylamide gel (nPAG) dosimeter that is intended for use with MRI to provide dosimetric data. The phantom has been improved by the inclusion of new components that are more realistic anatomically and exhibit CT values similar to those of the tissues they mimic. Component organs were made from 3D-printed molds developed from CT contours of a real patient and their radiodensities adjusted by varying the mass ratios of the PVCP hardener and softener during manufacture. To make the phantom more compatible with ultrasound imaging a graphite scatterer was mixed into some of the phantom components to produce a background speckle pattern. This provided contrast between the body and a moving anatomi...

中文翻译:

改进的腹部体模用于分数内图像引导验证

正在开发一种模拟人体呼吸的人体可动态压缩人体模型,以进行放射治疗中图像门控束传输的可能测试。聚氯乙烯增塑溶胶(PVCP)体模具有一个空腔,该空腔可包含可变形的常氧聚丙烯酰胺凝胶(nPAG)剂量计,该剂量计旨在与MRI一起使用以提供剂量学数据。幻影通过加入新的组件而得到了改进,这些新组件在解剖学上更加逼真,并且显示出与它们所模仿的组织相似的CT值。组件器官是由3D打印的模具制成的,该模具是根据实际患者的CT轮廓开发而成的,其射线密度可通过在制造过程中改变PVCP硬化剂和柔软剂的质量比进行调整。为了使体模与超声成像更加兼容,将石墨散射体混合到一些体模组件中,以产生背景斑点图案。这提供了身体与运动的解剖结构之间的对比。
更新日期:2020-07-03
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