Implantable devices have emerged as a promising industry. It is inevitable that these devices will require a power source to operate in vivo . Thus, to power implantable medical devices, biofuel cells (BFCs) that generate electricity using glucose without an external power supply have been considered. Although implantable BFCs have been developed for application in vivo , they are limited by their bulky electrodes and low power density. In the present study, we attempted to apply to living mice an implantable enzymatic BFC (EBFC) that was previously reported to be a high-power EBFC comprising carbon nanotube yarn electrodes. To improve their mechanical properties and for convenient implantation, the electrodes were coated with Nafion and twisted into a micro-sized, two-ply, one-body system. When the two-ply EBFC system was implanted in the abdominal cavity of mice, it provided a high-power density of 0.3 mW/cm ² . The two-ply EBFC system was injected through a needle using a syringe without surgery and the inflammatory response in vivo initially induced by the injection of the EBFC system was attenuated after 7 days, indicating the biocompatibility of the system in vivo .

中文翻译：

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两层碳纳米管纤维型酶促生物燃料电池植入小鼠。

植入式器械已成为一个有前途的行业。这些设备不可避免地需要电源才能运行体内 。因此，为了给可植入医疗设备供电，已经考虑了使用葡萄糖而无需外部电源来发电的生物燃料电池（BFC）。尽管已开发出可植入的BFC用于应用体内 ，它们受限于其庞大的电极和低功率密度。在本研究中，我们尝试将可植入的酶促BFC（EBFC）应用于活小鼠，该BFC先前据报道是包含碳纳米管纱线电极的高功率EBFC。为了改善它们的机械性能并方便植入，电极用Nafion涂层并扭曲成微型的两层单体系统。当将两层EBFC系统植入小鼠腹腔中时，它可提供0.3 mW / cm ²的高功率密度 。使用注射器将两层EBFC系统通过针头注射，无需手术和炎症反应体内 注射EBFC系统最初诱导的效果在7天后减弱，表明该系统具有生物相容性 体内 。