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Lightweight 1-photon miniscope for imaging in freely behaving animals at subcellular resolution.
IEEE Photonics Technology Letters ( IF 2.3 ) Pub Date : 2020-08-01 , DOI: 10.1109/lpt.2020.3004283
Arutyun Bagramyan

Miniaturization of imaging systems has become an important requirement for studying the brains of freely behaving animals (mice, birds, etc.). The author presents a 1-photon miniscope device with significant mechanical (weight: 1.3g, small size: 10mm $\times17$ mm $\times12$ mm) and optical (lateral resolution: 1 $\mu \text{m}$ , magnification: 12.5, etc.) advantages compared to existing systems. This device can be used to image and study fine brain structures and its design is well-suited for the incorporation of future generations of depth scanning, aberration correction, structured illumination and wireless approaches.

中文翻译:

轻量级 1 光子微型显微镜,用于以亚细胞分辨率对自由行为的动物进行成像。

成像系统的小型化已成为研究自由行为动物(小鼠、鸟类等)大脑的重要要求。作者展示了一个具有显着机械性能的单光子微型设备(重量:1.3g,小尺寸:10mm $\times17$ 毫米 $\times12$ mm) 和光学(横向分辨率:1 $\mu \text{m}$ , 放大倍数:12.5 等) 与现有系统相比的优势。该设备可用于对大脑的精细结构进行成像和研究,其设计非常适合结合未来的深度扫描、像差校正、结构化照明和无线方法。
更新日期:2020-08-01
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