This study is aimed at assessing the willingness to participate in the HIV vaccine trials and the associated factors among people who inject drugs (PWIDs) in Tanzania. Information about the willingness to participate and the associated factors was collected using interviewer-administered questionnaires at the medication treatment for opioid use disorder (MOUD) clinic in Dar es Salaam. Data analysis was performed using the IBM SPSS Statistic 20. The mean age of respondents was 36.7, and the standard deviation (SD) was ±7.2. The majority of respondents (68%) had primary education, and a high proportion of them were single (61.5%). More than one-third (37.9%) shared needles and syringes. Most (87.3%) had more than three sexual partners, and almost half (51.4%) did not use condoms during sexual intercourse with nonregular partners. About 63% had knowledge of HIV transmission while 27% had heard about HIV vaccine trials. Generally, 76% of the respondents expressed willingness to participate in future HIV vaccine trials regardless of prior knowledge of HIV vaccine trials. Willingness to participate in HIV vaccine trials was not associated with education level, people living with, knowledge about HIV transmission, awareness of HIV vaccine trials, sharing of syringe/needles, and number of sexual partners. Only older age (, , 2.6) and condom use (, , 0.97) showed an association with willingness. However, after performing logistic regression with factors at value ≤ 0.2 to ascertain the other factors on the effects of age, condom use, education level, and sharing of needles/syringes, the results were not statistically significant. Although participants reported a high willingness to participate in hypothetical HIV vaccine trials, no definitive conclusion can be drawn about the associated factors. Further studies with intensive educational programs are needed to investigate the factors on willingness to participate in actual HIV vaccine trials among PWIDs.

中文翻译：

---

坦桑尼亚达累斯萨拉姆注射毒品的人中是否愿意参加假想的HIV疫苗试验和相关因素。

这项研究旨在评估坦桑尼亚参加艾滋病毒疫苗试验的意愿以及相关因素。有关参与意愿和相关因素的信息是在达累斯萨拉姆的阿片类药物使用障碍（MOUD）诊所的药物治疗中使用由访调员管理的问卷收集的。使用IBM SPSS Statistic 20进行数据分析。受访者的平均年龄为36.7，标准差（SD）为±7.2。大多数受访者（68％）接受过初等教育，其中很大一部分是单身（61.5％）。超过三分之一（37.9％）共用针头和注射器。大多数（87.3％）拥有三个以上的性伴侣，几乎一半（51.4％）在与非常规伴侣进行性交时未使用安全套。大约63％的人了解HIV传播知识，而27％的人听说过HIV疫苗试验。通常，无论先前是否有HIV疫苗试验知识，有76％的受访者表示愿意参加未来的HIV疫苗试验。参加艾滋病毒疫苗试验的意愿与教育程度，与之相关的人，对艾滋病毒传播的知识，对艾滋病毒疫苗试验的认识，注射器/针头的共享以及性伴侣的数量都没有关联。仅年龄较大（有关艾滋病毒传播的知识，对艾滋病毒疫苗试验的了解，共用注射器/针头以及性伴侣的数量。仅年龄较大（有关艾滋病毒传播的知识，对艾滋病毒疫苗试验的了解，共用注射器/针头以及性伴侣的数量。仅年龄较大（， ， 2.6）和使用安全套（， ， 0.97）表示与意愿相关。但是，在对值≤0.2的因素进行逻辑回归以确定其他因素对年龄，安全套使用，受教育程度和共用针头/注射器的影响后，结果没有统计学意义。尽管参与者报告说愿意参加假设的HIV疫苗试验，但不能得出有关相关因素的明确结论。需要通过强化教育计划进行进一步研究，以调查参与PWID人群中实际HIV疫苗试验的意愿的因素。