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Dual role of splenic mononuclear and polymorphonuclear cells in the outcome of ciprofloxacin treatment of Salmonella enterica infections.
Journal of Antimicrobial Chemotherapy ( IF 3.9 ) Pub Date : 2020-07-02 , DOI: 10.1093/jac/dkaa249
P Kanvatirth 1 , O Rossi 1 , O Restif 1 , B A Blacklaws 1 , P Tonks 1 , A J Grant 1 , P Mastroeni 1
Affiliation  

To determine the immune cell populations associated with Salmonella enterica serovar Typhimurium before and after ciprofloxacin treatment using a murine model of systemic infection. The effect of depletion of immune cells associating with Salmonella on treatment outcome was also determined.

中文翻译:

脾脏单核细胞和多形核细胞在环丙沙星治疗肠炎沙门氏菌感染的结果中具有双重作用。

使用系统感染的小鼠模型,确定环丙沙星治疗前后沙门氏菌血清鼠伤寒沙门氏菌相关的免疫细胞群。还确定了与沙门氏菌相关的免疫细胞耗竭对治疗结果的影响。
更新日期:2020-07-02
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