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Biofabricated Nanostructures and Their Composites in Regenerative Medicine
ACS Applied Nano Materials ( IF 5.3 ) Pub Date : 2020-07-03 , DOI: 10.1021/acsanm.0c01164
Pooyan Makvandi 1, 2 , Matineh Ghomi 2 , Vinod V. T. Padil 3 , Faezeh Shalchy 4 , Milad Ashrafizadeh 5 , Sina Askarinejad 6 , Nahid Pourreza 2 , Ali Zarrabi 7, 8 , Ehsan Nazarzadeh Zare 9 , Mohamad Kooti 2 , Babak Mokhtari 2 , Assunta Borzacchiello 1 , Franklin R. Tay 10
Affiliation  

Biosynthesis of nanomaterials is gaining attention as a sustainable, environmentally friendly, and reliable method for manufacturing a extensive array of nanostructures, such as metal/metal oxides and organic and hybrid materials. Green synthesis is considered a crucial tool to reduce the harsh effects associated with conventional synthesis. Nanocomposite materials containing biosynthesized nanostructures are highly sought after in regenerative medicine. In the present Review, biosynthesis of metal/metal oxides and carbon-based nanomaterials using microorganisms (e.g., bacteria and fungi) and natural compounds (e.g., polysaccharides, proteins, fruit juices, and plant extracts) is highlighted. The toxicity of biosynthesized nanoparticles for biomedical application is also reviewed in depth. The applications of bionanocomposites prepared from these ecofriendly nanoparticles in tissue engineering are reviewed to provide readers with a background for future studies.

中文翻译:

再生医学中的生物预制纳米结构及其复合材料

纳米材料的生物合成作为一种可持续的,环保的,可靠的方法,已被广泛用于制造各种纳米结构,例如金属/金属氧化物以及有机和杂化材料,因此受到关注。绿色合成被认为是减少与常规合成相关的严酷影响的关键工具。包含生物合成的纳米结构的纳米复合材料在再生医学中非常受追捧。在本综述中,强调了利用微生物(例如细菌和真菌)和天然化合物(例如多糖,蛋白质,果汁和植物提取物)生物合成金属/金属氧化物和碳基纳米材料。还深入综述了生物合成的纳米颗粒在生物医学应用中的毒性。
更新日期:2020-07-24
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