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Pseudomonas Phage PaBG-A Jumbo Member of an Old Parasite Family.
Viruses ( IF 3.8 ) Pub Date : 2020-07-03 , DOI: 10.3390/v12070721
Peter Evseev 1 , Nina Sykilinda 1 , Anna Gorshkova 2 , Lidia Kurochkina 3 , Rustam Ziganshin 1 , Valentin Drucker 2 , Konstantin Miroshnikov 1
Affiliation  

Bacteriophage PaBG is a jumbo Myoviridae phage isolated from water of Lake Baikal. This phage has limited diffusion ability and thermal stability and infects a narrow range of Pseudomonas aeruginosa strains. Therefore, it is hardly suitable for phage therapy applications. However, the analysis of the genome of PaBG presents a number of insights into the evolutionary history of this phage and jumbo phages in general. We suggest that PaBG represents an ancient group distantly related to all known classified families of phages.

中文翻译:


假单胞菌噬菌体 PaBG-古老寄生虫家族的巨型成员。



噬菌体 PaBG 是从贝加尔湖水中分离出来的巨型肌病毒科噬菌体。该噬菌体具有有限的扩散能力和热稳定性,并且感染小范围的铜绿假单胞菌菌株。因此,它几乎不适合噬菌体治疗应用。然而,对 PaBG 基因组的分析为该噬菌体和巨型噬菌体的进化历史提供了一些见解。我们认为 PaBG 代表了一个与所有已知的噬菌体分类家族有远亲关系的古老群体。
更新日期:2020-07-03
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