Mercapto-substituted 1,2,4-triazoles are very interesting compounds as they play an important role in chemopreventive and chemotherapeutic effects on cancer. In recent decades, literature has been enriched with sulfur- and nitrogen-containing heterocycles which are used as a basic nucleus of different heterocyclic compounds with various biological applications in medicine and also occupy a huge part of natural products. Therefore, we shed, herein, more light on the synthesis of this interesting class and its application as a biologically active moiety. They might also be suitable as antiviral and anti-infective drugs.

中文翻译：

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1,2,4-三唑硫酮的化学和生物活性——抗病毒和抗感染药物

巯基取代的 1,2,4-三唑是非常有趣的化合物，因为它们在对癌症的化学预防和化学治疗作用中起着重要作用。近几十年来，文献中丰富了含硫和含氮杂环，它们被用作不同杂环化合物的基本核，在医学上具有各种生物学应用，并且在天然产物中占据了很大一部分。因此，我们在本文中更多地阐明了这一有趣类别的合成及其作为生物活性部分的应用。它们也可能适合作为抗病毒和抗感染药物。