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Marine Excitatory Amino Acids: Structure, Properties, Biosynthesis and Recent Approaches to Their Syntheses
Molecules ( IF 4.6 ) Pub Date : 2020-07-03 , DOI: 10.3390/molecules25133049
Valentin A Stonik 1 , Inna V Stonik 2
Affiliation  

This review considers the results of recent studies on marine excitatory amino acids, including kainic acid, domoic acid, dysiherbaine, and neodysiherbaine A, known as potent agonists of one of subtypes of glutamate receptors, the so-called kainate receptors. Novel information, particularly concerning biosynthesis, environmental roles, biological action, and syntheses of these marine metabolites, obtained mainly in last 10–15 years, is summarized. The goal of the review was not only to discuss recently obtained data, but also to provide a brief introduction to the field of marine excitatory amino acid research.

中文翻译:

海洋兴奋性氨基酸:结构、性质、生物合成及其合成方法

本综述考虑了最近对海洋兴奋性氨基酸的研究结果,包括海藻酸、海藻酸、dysiherbaine 和neodysiherbaine A,它们被称为谷氨酸受体亚型之一(即所谓的红藻氨酸受体)的有效激动剂。总结了主要在过去 10-15 年中获得的新信息,特别是关于这些海洋代谢物的生物合成、环境作用、生物作用和合成。该综述的目的不仅是讨论最近获得的数据,而且是对海洋兴奋性氨基酸研究领域的简要介绍。
更新日期:2020-07-03
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