Pregnancy is a period of serial metabolic and hormonal changes in the woman’s body. Factors such as circulating adipokines affect the fetal period and may cause long-term changes in metabolic pathways at the cellular, tissue, or organ level. The nutritional status of the pregnant woman affects the course of pregnancy, delivery, and confinement, as well as the health of the offspring following birth and in subsequent years. Adipokine hormones essential for modulating metabolism during pregnancy include adiponectin and leptin. This study aimed to assess maternal anthropometric parameters and plasma concentrations of specific adipokines as predictive measures of newborn birth weight, birth length, and ponderal index. Anthropometric measurements (prepregnancy body weight and height) were obtained from 168 surveyed Polish women. Data related to the birth parameters of 168 newborns (body length and mass) were derived from clinical records. Circulating maternal adiponectin and leptin levels at birth were determined. Significant correlations between newborn birth weight and maternal prepregnancy body mass index (p < 0.05) or maternal weight gain during pregnancy (p < 0.05) were observed. Women with below normal weight gain during pregnancy were more likely to give birth to newborns with significantly lower birth weight than women with excessive weight gain during pregnancy (p < 0.05). Maternal plasma concentrations of leptin were significantly related to prepregnancy maternal body mass index (p < 0.05), and concentrations of adiponectin and leptin were significantly related to weight gain during pregnancy (p < 0.05). However, they did not affect the birth parameters of the newborn.

中文翻译：

---

产妇人体测量因素和循环脂肪因子作为出生体重和身长的预测指标。

怀孕是妇女体内一系列新陈代谢和激素变化的时期。诸如循环脂肪因子等因素会影响胎儿时期，并可能导致细胞，组织或器官水平的代谢途径发生长期变化。孕妇的营养状况会影响怀孕，分娩和分娩的过程，以及分娩后及其后几年的后代健康。在怀孕期间调节代谢必不可少的脂肪因子激素包括脂联素和瘦素。这项研究旨在评估孕妇的人体测量学参数和特定脂肪因子的血浆浓度，作为新生儿出生体重，出生长度和子宫指数的预测指标。从168名接受调查的波兰妇女那里获得了人体测量值（妊娠体重和身高）。与168名新生儿的出生参数（体长和体重）有关的数据来自临床记录。确定出生时循环的孕妇脂联素和瘦素水平。新生儿出生体重与母亲孕期体重指数之间的显着相关性（p <0.05）或孕期孕妇体重增加（p <0.05）。与怀孕期间体重增加过多的妇女相比，怀孕期间体重增加低于正常的妇女更容易生出出生体重明显较低的新生儿（p <0.05）。孕妇血浆中瘦素的浓度与孕前孕妇体重指数显着相关（p <0.05），脂联素和瘦素的浓度与妊娠期体重增加显着相关（p <0.05）。但是，它们不会影响新生儿的出生参数。