A minimally invasive clinical model to test sunscreen toxicity based on oxidative stress levels using microbiopsy and confocal microscopy - a proof of concept study.,International Journal of Cosmetic Science

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A minimally invasive clinical model to test sunscreen toxicity based on oxidative stress levels using microbiopsy and confocal microscopy - a proof of concept study.
International Journal of Cosmetic Science ( IF 2.7 ) Pub Date : 2020-07-03 , DOI: 10.1111/ics.12646
Miko Yamada ₁ , Lynlee L Lin ₂ , Lydia Y T Hang ₂ , Paul J Belt ₃ , H Peter Soyer ₂ , Anthony P Raphael ₁ , Tarl W Prow ₁

Affiliation

This proof‐of‐concept study demonstrated that using minimally invasive skin microsampling could enable significantly higher throughput of cosmetic testing in volunteers than conventional biopsy. Nanoparticle sunscreen was used as a model to test toxicity based on oxidative stress using microbiopsy and confocal imaging.

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