Adult‐onset asthma and chronic obstructive pulmonary disease (COPD) are heterogeneous diseases caused by complex gene‐environment interactions. A functional single nucleotide polymorphism of cadherin‐related family member 3 (CDHR3), known as a receptor of rhinovirus‐C, is associated with childhood‐onset asthma especially in atopic individuals.

中文翻译：

---

CDHR3 对成人哮喘和 COPD 发病的遗传影响

成人哮喘和慢性阻塞性肺疾病（COPD）是由复杂的基因-环境相互作用引起的异质性疾病。钙粘蛋白相关家族成员 3 (CDHR3) 的功能性单核苷酸多态性，被称为鼻病毒 C 的受体，与儿童期哮喘特别是特应性个体有关。