The study examined the degradation of riot control agents (RCAs): 2-chloroacetophenone (CN), 2-chlorobenzalmalononitrile (CS), and capsaicin, using the Reactive Skin Decontamination Lotion Kit (RSDL® ) lotion and evaluated the the direct liquid phase reactivity of the RSDL lotion component with each RCA. RSDL lotion was mixed with the selected RCAs at different molar ratios. Reactivity of the active ingredient potassium 2,3-butanedione monoximate (KBDO) with the RCA was observed for one hour. Samples of 10 µL were taken and quenched, analyzed for residual RCA using LC-MS. CN, was degraded at molar ratios of two and above in less than 2 minutes. At a molar ratio of 1:1 KBDO:CN, ∼90% of CN was degraded within 2 minutes, the remaining 10% residual CN was observed for one hour without any change. CS, degradation of more than 68% of CS was achieved at 20:1 molar ratio of KBDO:CS within 1 hour of reaction time. For capsaicin, no degradation was observed regardless of the higher molar ratios of up to 20:1 and longer reaction times of up to one hour. This study provides evaluation of neutralizing action of the RSDL lotion without assessment of the physical removal component by the RSDL Kit.

中文翻译：

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RSDL®（反应性皮肤去污乳液套件）乳液成分对防暴剂的体外去污功效：辣椒素、MaceTM (CN) 和 CS

该研究使用反应性皮肤去污乳液套件 (RSDL®) 乳液检查了防暴剂 (RCA)：2-氯苯乙酮 (CN)、2-氯苯扎丙二腈 (CS) 和辣椒素的降解，并评估了直接液相反应性每个 RCA 的 RSDL 乳液成分。RSDL 洗剂与选定的 RCA 以不同的摩尔比混合。观察活性成分 2,3-丁二酮一肟酸钾 (KBDO) 与 RCA 的反应性一小时。取 10 µL 样品并淬灭，使用 LC-MS 分析残留的 RCA。CN 以 2 及以上的摩尔比在不到 2 分钟的时间内降解。在 1:1 KBDO:CN 的摩尔比下，约 90% 的 CN 在 2 分钟内降解，剩余的 10% 残留 CN 观察 1 小时后没有任何变化。CS，在 20:1 的 KBDO:CS 摩尔比下，反应时间的 1 小时内实现了超过 68% 的 CS 降解。对于辣椒素，无论摩尔比高达 20:1，反应时间长达一小时，都没有观察到降解。本研究评估 RSDL 洗剂的中和作用，而无需评估 RSDL 试剂盒的物理去除成分。