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A near-infrared fluorescent probe for imaging of nitroxyl in living cells.
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy ( IF 4.3 ) Pub Date : 2020-07-03 , DOI: 10.1016/j.saa.2020.118680
Zhipeng Liu 1 , Qian Sun 1
Affiliation  

A BODIPY-based NIR fluorescent probe, NitroxylBDP, for the rapid and specific, detection of HNO has been designed and synthesized. The merits of NIR fluorescence, and stable fluorescence output against pH changes, and good membrane permeability, enable the probe to serve as an ideal indicator for tracking HNO in living systems.



中文翻译:

一种近红外荧光探针,用于在活细胞中对硝氧基成像。

设计并合成了一种基于BODIPY的NIR荧光探针NitroxylBDP,用于快速,特异性地检测HNO。NIR荧光的优点,针对pH值变化的稳定荧光输出以及良好的膜渗透性,使该探头成为追踪活体系统中HNO的理想指标。

更新日期:2020-07-08
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