Micro-mesoporous Zn–OH/HZSM-5 catalysts were prepared by alkaline treatment and Zn modification of HZSM-5 zeolite for the synthesis of pyridine bases from ethanol, methanol and ammonia through a fixed bed reactor. It has been discovered that a large number of bigger micropores and mesopores were produced because of the disappearance of the neighboring walls of two bigger micropores and crossing walls of three micropores. At the same time, the strong acid sites of HZSM-5 zeolites became weaker and fewer due to desilication and dealumination. It was believed that the micro-mesoporous structure of the catalysts, the amount and strength of the weak and medium acid sites, as well as suitable ethanol/methanol/ammonia ratio were the key factors that affected the formation of pyridine bases from alcohol and ammonia. The highest yield and selectivity of pyridine bases were 50.27% and 59.45% over Zn-5-OH/HZ5 catalyst at 410 °C, WHSV = 2.0 h⁻¹ and C₂H₅OH/CH₃OH/NH₃ = 2/1/3 (mol) after amination, dehydrogenation, cycloaddition and deamination from ethanol, methanol and ammonia.

通过碱处理和Zn改性HZSM-5沸石制备了微介孔的Zn-OH / HZSM-5催化剂，用于通过固定床反应器从乙醇，甲醇和氨合成吡啶碱。已经发现，由于两个较大的微孔的相邻壁和三个微孔的交叉壁的消失，产生了大量的较大的微孔和中孔。同时，由于脱硅和脱铝作用，HZSM-5沸石的强酸位变得越来越弱。据认为，催化剂的微介孔结构，弱酸和中等酸位的数量和强度以及合适的乙醇/甲醇/氨比是影响由醇和氨形成吡啶碱的关键因素。 在氨基化，脱氢，环加成和从乙醇，甲醇和氨脱氨基后，^-1和C ₂ H ₅ OH / CH ₃ OH / NH ₃ = 2/1/3（mol）。