Background/Objective

Patients with head and neck cancer (HNC) have some problems such as dysfunction of breathing, eating, and/or speaking. The aim of this study was to examine efficacy of the stress management program for HNC patients (SMAP-HNC) compared with usual care (UC).

Method

We conducted a pilot study of SMAP-HNC for depressive HNC patients between January 2016 and March 2018. The program contains psychoeducation, stress coping training, and operant reinforcement. The outcome measure was the Hospital Anxiety and Depression Scale (HADS), Functional Assessment of Cancer Therapy (FACT), and Brief Coping Inventory (COPE).

Results

Twenty patients were randomly assigned to SMAP-HNC and UC group. Although a small sample sizes, there was no significant difference of depression score change between SMAP-HNC and UC group (Hedges’d g -0.83; 95% CI -1.80 to 0.13).

Conclusions

It was the first study to conduct stress management program for HNC patients. Unfortunately, our trial designed as a randomized controlled trial is underpowered to make conclusion as to the efficacy of SMAP-HNC. However, there are some valuable suggestions to modify the stress management program in future.

中文翻译：

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压力管理计划对晚期头颈癌抑郁患者的疗效：一项单中心试点研究

背景/目标

头颈癌 (HNC) 患者存在呼吸、进食和/或说话功能障碍等问题。本研究的目的是比较 HNC 患者的压力管理计划 (SMAP-HNC) 与常规护理 (UC) 的效果。

方法

我们在 2016 年 1 月至 2018 年 3 月期间对抑郁 HNC 患者进行了 SMAP-HNC 试点研究。该计划包含心理教育、压力应对训练和操作性强化。结果测量是医院焦虑和抑郁量表（HADS）、癌症治疗功能评估（FACT）和简要应对量表（COPE）。

结果

20 名患者被随机分配到 SMAP-HNC 和 UC 组。尽管样本量很小，但 SMAP-HNC 和 UC 组之间的抑郁评分变化没有显着差异（Hedges'd g -0.83；95% CI -1.80 至 0.13）。

结论

这是第一项针对 HNC 患者进行压力管理计划的研究。不幸的是，我们设计为随机对照试验的试验不足以对 SMAP-HNC 的疗效作出结论。但是，有一些有价值的建议可以在未来修改压力管理计划。