Organisms need to constantly inform their cellular machinery about the biochemical and physical status of their surroundings to adapt and thrive. While some external signals are also sensed intracellularly, a considerable share of external information is registered already at the plasma membrane (PM). Receptor kinases (RKs) are crucial for plant cells to integrate such cues from the environment, from microbes, or from other cells to coordinate their physiological response and their development. Early studies on RK signaling depicted the path from external signal to internal response in a linear fashion, but recent findings show that these cellular information highways are highly interconnected and pass signals through molecular intersections. In this review, we first discuss how individual RKs simultaneously contribute to the transduction and deconvolution of a multitude of signals by controlled assembly into diverse RK complexes, exemplified by FERONIA signaling versatility. We then elaborate on how cells can exert highly localized control over the assembly, interaction and composition of such complexes in order to attain essential cellular output specificity.

有机体需要不断地告知其细胞机械其周围环境的生化和物理状况，以适应和发展。虽然还可以在细胞内感测到一些外部信号，但相当一部分外部信息已在质膜（PM）处记录下来。受体激酶（RKs）对于植物细胞整合来自环境，微生物或其他细胞的此类线索以协调其生理反应和发育至关重要。RK信号的早期研究以线性方式描绘了从外部信号到内部响应的路径，但是最近的发现表明这些细胞信息通道高度互连，并通过分子交叉点传递信号。在这篇评论中 我们首先讨论各个RK如何同时通过受控组装成不同的RK复合物，同时促进多种信号的转导和去卷积，例如FERONIA信号多功能性。然后，我们详细阐述了细胞如何对此类复合物的组装，相互作用和组成施加高度局部控制，以实现基本的细胞输出特异性。