The aim of this study was to determine dietary exposure to ochratoxin A (OTA) in Turkish adults. In this study, 500 food samples (50 rice, 50 wheat bread, 50 pasta, 50 raisins, 50 dried figs, 50 pistachios, 50 hazelnuts, 50 almonds, 50 chilli, 25 coffee, and 25 cocoa) collected from Turkey were analysed with a high-performance liquid chromatography (HPLC) method. Moreover, a total of 370 analytical results (110 cereal-based snacks, 95 wine, 35 beer, and 130 chocolate) collected from our previous observations were also used in the evaluation of exposure estimates. OTA was found in 52% of cocoa, 42% of raisins, 40% of coffee, 34% of chilli, 14% of dried figs, 10% of pasta, 8% of pistachios, 6% of wheat bread, 4% of rice, and 4% of hazelnuts. The chronic dietary exposure to OTA for Turkish adults, using lower bound (LB) and upper bound (UB) concentrations, varied from 0.683 to 4.487 ng/kg body weight (b.w.) per week for mean estimate and from 3.976 to 5.760 ng/kg b.w. per week for the 95th percentile (P95) estimate. Cereals and cereal-based products made the largest contribution (75.3–85.7%) to OTA exposure. Both mean and P95 chronic exposure to OTA were greatly below the tolerable weekly intake of 120 ng/kg b.w. per week and thus not a health concern for Turkish adults.

中文翻译：

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土耳其中部安纳托利亚地区of曲毒素A的饮食暴露初步评估。

这项研究的目的是确定土耳其成年人饮食中曲毒素A（OTA）的摄入量。在这项研究中，分析了从土耳其收集的500种食物样品（50种大米，50种小麦面包，50种意大利面，50种葡萄干，50种无花果干，50种开心果，50种榛子，50种杏仁，50种辣椒，25种咖啡和25种可可）。高效液相色谱（HPLC）方法。此外，从我们先前的观察中收集到的总共370个分析结果（110种谷类食品，95种葡萄酒，35种啤酒和130种巧克力）也被用于评估暴露估计。在52％的可可粉，42％的葡萄干，40％的咖啡，34％的辣椒，14％的无花果干，10％的意大利面，8％的开心果，6％的小麦面包，6％的大米中发现了OTA。 ，以及4％的榛子。土耳其成年人长期通过OTA饮食饮食，使用下限（LB）和上限（UB）浓度，每周平均估计值从0.683至4.487 ng / kg体重（bw）变化，而第95个百分位数（P95）从每周3.976至5.760 ng / kg bw估计。谷物和谷类产品对OTA的暴露贡献最大（75.3–85.7％）。长期暴露于OTA的平均值和P95均大大低于每周可耐受的120 ng / kg bw的每周摄入量，因此土耳其成年人无需担心健康。