Few studies have investigated the prevalence of frailty in the Australian general population. This study determined the prevalence of frailty in a population-based sample of older adults and examined the relationship between frailty and comorbid conditions. Men (n = 347) and women (n = 360) aged ≥ 60 year from the Geelong Osteoporosis Study (GOS) were assessed between 2016–2019 and 2011–2014, respectively. Frailty was identified using a modified Fried frailty phenotype. Prevalence estimates were standardised to the 2011 Australian population. Kruskal–Wallis test and χ² test were used to analyse data. For women, mean standardised prevalence estimates were 18.3% (14.1–22.5) for frail, 54.1% (47.3–60.8) pre-frail and 22.9% (18.9–26.8) robust. Corresponding estimates for men were 13.1% (9.8–16.3) frail, 47.8% (42.0–53.6) pre-frail and 27.3% (22.7–31.8) robust. Women who were frail were older, shorter, tended to have a higher body mass index (BMI) and used more medications compared to other groups. Compared to robust women, those who were frail were more likely to have cardio-metabolic (OR 3.5 (0.7–20.0)), pulmonary (OR 3.5 (1.5–8.4)) and musculoskeletal (OR 10.1 (2.1–48.0)) conditions. Frail men were older, had a higher BMI and were more likely to have musculoskeletal conditions (OR 5.8 (2.8–12.3)) and tended to be from a lower SES. No further associations were observed. This study reported the prevalence of frail and pre-frail individuals in a population-based sample of Australian men and women. Frailty was associated with musculoskeletal conditions for both men and women; however, associations with cardio-metabolic and pulmonary comorbidities were evident in women only.

很少有研究调查澳大利亚普通人群中虚弱的患病率。这项研究确定了以人群为基础的老年人中脆弱的患病率，并研究了脆弱与共病状况之间的关系。 吉朗骨质疏松症研究（GOS）分别对年龄≥60岁的男性（n  = 347）和女性（n = 360）进行了评估，时间分别为2016-2019年和2011-2014年。使用改良的Fried脆弱体表型鉴定脆弱体。患病率估算是针对2011年澳大利亚人口的。Kruskal-Wallis检验和χ ²测试用于分析数据。对于女性，体弱者的平均标准患病率估计值为18.3％（14.1–22.5），体弱者为54.1％（47.3–60.8）和22.9％（18.9–26.8）稳健。男性的相应估计值是：身体虚弱的人占13.1％（9.8-16.3），身体虚弱的人占47.8％（42.0-53.6），身体健壮的人占27.3％（22.7-31.8）。与其他人群相比，身体虚弱的女性年龄更大，身材矮小，往往具有更高的体重指数（BMI）并使用更多的药物。与健壮的女性相比，那些体弱的女性更容易出现心脏代谢性疾病（OR 3.5（0.7–20.0）），肺部疾病（OR 3.5（1.5–8.4））和肌肉骨骼疾病（OR 10.1（2.1–48.0））。体弱的男人年龄较大，BMI较高，更可能具有肌肉骨骼疾病（OR 5.8（2.8-12.3）），并且往往来自较低的SES。没有观察到进一步的关联。这项研究报告了以人口为基础的澳大利亚男性和女性样本中体弱者和体弱者的患病率。脆弱与男性和女性的肌肉骨骼状况有关。然而，仅在女性中与心脏代谢和肺部合并症相关。