Quantitative phase microscopy (QPM) has emerged as an important tool for material metrology and biological imaging. For broader adoption in those applications, we have proposed and demonstrated a new portable off-axis QPM method, which works in both transmission and reflection modes to meet different sample measurement requirements. The temporal and spatial sensitivities of our system, as quantified by optical path-length difference values, are 0.65 nm and 1.04 nm, respectively. To demonstrate its applicability for a wide range of applications, we deployed our system for profiling transistor gold electrode samples, observing red blood cell membrane fluctuations, imaging living cells flowing in a microfluidic chip, etc. Our portable QPM system has a low-cost design and involves a simple and robust phase-retrieval algorithm that we envision will allow for broader deployment at different environmental settings, including in resource-limited sites and integration with other metrology or imaging modalities.

中文翻译：

---

用于材料计量和生物成像的便携式定量相位显微镜

定量相位显微镜 (QPM) 已成为材料计量学和生物成像的重要工具。为了在这些应用中更广泛地采用，我们提出并展示了一种新的便携式离轴 QPM 方法，该方法可在透射和反射模式下工作，以满足不同的样品测量要求。我们系统的时间和空间灵敏度，由光程长度差值量化，分别为 0.65 nm 和 1.04 nm。为了证明其在广泛应用中的适用性，我们部署了我们的系统来分析晶体管金电极样品、观察红细胞膜波动、对微流体芯片中流动的活细胞进行成像等。