Cutaneous Lupus Erythematosus (CLE) is a clinically diverse group of autoimmune skin diseases with shared histological features of interface dermatitis and autoantibodies deposited at the dermal–epidermal junction. Various genetic and environmental triggers of CLE promote infiltration of T cells, B cells, neutrophils, antigen presenting cells, and NK cells into lesional skin. In this mini-review, we will discuss the clinical features of CLE, insights into CLE immunopathogenesis, and novel treatment approaches.

中文翻译：

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皮肤红斑狼疮免疫病理的最新见解。

皮肤红斑狼疮（CLE）是临床上多种多样的自身免疫性皮肤病，具有交界面性皮炎和沉积在真皮-表皮交界处的自身抗体的共同组织学特征。CLE的各种遗传和环境诱因促进T细胞，B细胞，嗜中性粒细胞，抗原呈递细胞和NK细胞向病变皮肤的浸润。在本微型审查中，我们将讨论CLE的临床特征，对CLE免疫发病机制的见识以及新颖的治疗方法。