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Cover Feature: Addition of Highly Polarized Organometallic Compounds to N‐tert‐Butanesulfinyl Imines in Deep Eutectic Solvents under Air: Preparation of Chiral Amines of Pharmaceutical Interest (ChemSusChem 14/2020)
ChemSusChem ( IF 7.5 ) Pub Date : 2020-07-02 , DOI: 10.1002/cssc.202001513
Luciana Cicco 1 , Antonio Salomone 2 , Paola Vitale 1 , Nicolás Ríos‐Lombardía 3 , Javier González‐Sabín 3 , Joaquín García‐Álvarez 4 , Filippo M. Perna 1 , Vito Capriati 1, 5
Affiliation  

The Cover Feature shows the preparation of highly enantioenriched chiral amines of pharmaceutical interest by chemoselective addition of organolithiums or Grignard reagents to chiral sulfinyl imines in the biodegradable d ‐sorbitol/choline chloride eutectic mixture at ambient temperature and under aerobic conditions. More information can be found in the Communication by L. Cicco et al. on page 3583 in Issue 14, 2020 (DOI: 10.1002/cssc.202001142).
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中文翻译:

封面人物:空气中深共晶溶剂中的N-叔丁烷亚磺酰基亚胺中添加高极性有机金属化合物:制备具有药用价值的手性胺(ChemSusChem 14/2020)

封面功能显示了在环境温度和好氧条件下,通过将有机锂或格氏试剂化学选择性地添加到可生物降解的d-山梨糖醇/氯化胆碱共晶混合物中的手性亚砜亚胺中,制备高度对映体富集的具有药用价值的手性胺。可以在L. Cicco等人的来文中找到更多信息。就在第14年,2020年3583页(:10.1002 / cssc.202001142 DOI)。
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更新日期:2020-07-22
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