The ongoing pandemic has stimulated study of the Renin Angiotensin Aldosterone System (RAAS), and how it can be manipulated to treat COVID-19. Studies are examining whether drugs that act on the RAAS system might be useful to treat COVID-19. COVID-19 and the RAAS are closely linked both in infection and in possible post-infection inflammatory cascades. We detail the Physiology and Pharmacology of the RAAS including the effects of aldosterone and atrial natriuretic peptide. It is appropriate that the theoretical benefits of modulation of the RAAS should be considered based on available knowledge of the complexity of the system. In this short review we have tried to explain the actions of the angiotensin family of peptides and produce a relatively simple model and diagrammatic summary of the RAAS and the possible sites of intervention.

持续的大流行刺激了肾素血管紧张素醛固酮系统（RAAS）的研究，以及如何对其进行操纵以治疗COVID-19。研究正在研究作用于RAAS系统的药物是否可能对治疗COVID-19有用。COVID-19和RAAS在感染和可能的感染后炎症级联反应中都紧密相连。我们详细介绍了生理学和PRAAS的药物学包括醛固酮和心钠素的作用。应当基于对系统复杂性的现有知识来考虑对RAAS进行调制的理论优势。在这篇简短的综述中，我们试图解释血管紧张素家族肽的作用，并给出相对简单的RAAS模型和图解摘要以及可能的干预部位。