Effective cancer treatment remains a significant challenge in human healthcare. Although many different types of cancer therapy have been tested, scientists have now concluded that combinations of drugs, or drugs plus gene therapy, can target multiple pathways to fight cancer. Nanovehicles can increase drug uptake inside tumor cells, improve biodistribution and accumulation at tumor sites. The ability to deliver two or more anticancer drugs, genes, among others, at the same time and place will increase therapeutic effects while decreasing side effects and reducing the risk of multidrug resistance. This review discusses the advantages of nano-based co-delivery methods in cancer therapy, summarizes the common types of nanovehicles and their preparation methods, and covers some recent co-delivery studies in detail.

有效的癌症治疗仍然是人类医疗保健领域的重大挑战。尽管已经测试了许多不同类型的癌症疗法，但科学家们现在得出结论，药物组合或药物加基因疗法可以针对多种途径来对抗癌症。纳米载体可以增加肿瘤细胞内的药物吸收，改善肿瘤部位的生物分布和积累。在同一时间和地点输送两种或多种抗癌药物、基因等的能力将增加治疗效果，同时减少副作用并降低多药耐药性的风险。本综述讨论了基于纳米的共递送方法在癌症治疗中的优势，总结了纳米载体的常见类型及其制备方法，并详细涵盖了最近的一些共递送研究。