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Rubbing Out Leukemia Stem Cells by Erasing the Eraser.
Cell Stem Cell ( IF 23.9 ) Pub Date : 2020-07-02 , DOI: 10.1016/j.stem.2020.06.009
Yuanming Cheng 1 , Hanzhi Luo 1 , Michael G Kharas 1
Affiliation  

In this issue of Cell Stem Cell, Shen et al. (2020) and Wang et al. (2020) independently identify the essential function of m6A demethylase ALKBH5 in maintaining myeloid leukemia stem cells. These studies expand the regulators of the epitranscriptome that are required for acute myeloid leukemia (AML) development.



中文翻译:

通过擦除橡皮擦擦掉白血病干细胞。

在本期Cell Stem Cell中,Shen 等人。(2020)和王等人。(2020) 独立鉴定了 m 6 A 去甲基化酶 ALKBH5 在维持髓性白血病干细胞中的基本功能。这些研究扩展了急性髓性白血病 (AML) 发展所需的表观转录组调节因子。

更新日期:2020-07-02
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