Objective

The present report aimed to document the clinical features of a case of Marshall-Smith syndrome (MSS), an extremely rare embryonic developmental disorder with associated craniosynostosis.

Patient and method

We presented herein a case of a 2-year-old female patient with MSS who underwent fronto-orbital advancement for multisuture craniosynostosis.

Results

The patient’s proptosis improved after surgery, and no further surgical intervention was required for corneal exposure. A second FOA followed by revision tarsorrhaphy further improved eye closure.

Conclusion

Surgical procedures to correct dysplastic features and limit neurological impairment are a worthwhile supportive treatment for improving the quality of life and general condition of patients with MSS.

中文翻译：

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马歇尔-史密斯综合症患者的眼眶进展：一例病例报告并复习文献。

目的

本报告旨在记录马歇尔-史密斯综合征（MSS）的临床特征，该综合征是一种极少见的伴有颅骨前突的胚胎发育障碍。

患者和方法

我们在此介绍了一名2岁的MSS女性患者，该患者因多缝颅窦结扎术接受了眶眶前移。

结果

手术后患者的眼球好转，角膜暴露不需要进一步的手术干预。再次FOA，然后进行睑环翻修，进一步改善了眼睛的闭合性。

结论

纠正不典型增生特征和限制神经系统损伤的外科手术程序，对于改善MSS患者的生活质量和一般状况是一种值得支持的治疗方法。