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Cetylpyridinium bromide/montmorillonite-graphene oxide composite with good antibacterial activity.
Biomedical Materials ( IF 3.9 ) Pub Date : 2020-06-30 , DOI: 10.1088/1748-605x/ab8440
Haoping Wu 1 , Yayuan Yan , Jing Feng , Jingxian Zhang , Suiping Deng , Xiang Cai , Langhuan Huang , Xiaobao Xie , Qingshan Shi , Shaozao Tan
Affiliation  

In this study, a cetylpyridinium bromide (CPB)/montmorillonite-graphene oxide (GM) composite (GM-CPB) was prepared by loading CPB in a carrier of GM. The chemical structure, elemental composition, morphology, thermogravimetric analysis, antibacterial activity, sustained release property and cytotoxicity were analyzed. The loading rate of CPB in a GM carrier was higher than that of the graphene oxide (GO) carrier under the same loading condition. The antibacterial activity and sustained release performance of GM-CPB were also better than that of GO-CPB; furthermore, GM-CPB showed lower cytotoxicity than CPB.

中文翻译:

溴化十六烷基吡啶/蒙脱石-氧化石墨烯复合物具有良好的抗菌活性。

在这项研究中,通过将 CPB 负载在 GM 载体中制备了十六烷基溴化吡啶 (CPB)/蒙脱石-氧化石墨烯 (GM) 复合材料 (GM-CPB)。对其化学结构、元素组成、形貌、热重分析、抗菌活性、缓释性和细胞毒性进行了分析。在相同的负载条件下,CPB 在 GM 载体中的负载率高于氧化石墨烯 (GO) 载体。GM-CPB的抗菌活性和缓释性能也优于GO-CPB;此外,GM-CPB 显示出比 CPB 更低的细胞毒性。
更新日期:2020-07-01
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