This study was conducted to evaluate antimicrobial activity of orthodontic elastomeric chains (OECs) coated with chlorhexidine (CHX) hexametaphosphate (HMP) nanoparticles and its effect on force decay. OECs were coated with CHX-HMP-5 (5 mM CHX and HMP), CHX-HMP-1 (1 mM CHX and HMP) nanoparticle colloidal solutions, CHX-5 (5 mM CHX) and CHX-1 (1 mM CHX) solutions. Release of CHX from coated OECs was evaluated over 28 days. Antimicrobial activity of the eluate collected on day 1 was tested against Streptococcus mutans and Lactobacillus rhamnosus by measuring the zone of inhibition after 4 days. OECs were observed by scanning electron microscope (SEM) to observe surface characteristics comparing: (1) uncoated and coated OECs and (2) before and after release of CHX. Force decay of OECs were measured over 28 days. SEM analysis showed that OECs were coated with nanoparticles. OECs coated with CHX-HMP-5 and CHX-HMP-1 released CHX over 28 days. The eluate from the coated O...

中文翻译：

---

洗必泰六偏磷酸盐纳米颗粒涂层对正畸弹性链的体外抗菌活性评估

进行这项研究以评估涂有洗必泰（CHX）六偏磷酸盐（HMP）纳米颗粒的正畸弹性链（OEC）的抗菌活性及其对力衰减的影响。OEC涂有CHX-HMP-5（5 mM CHX和HMP），CHX-HMP-1（1 mM CHX和HMP）纳米胶体溶液，CHX-5（5 mM CHX）和CHX-1（1 mM CHX）解决方案。在28天内评估了CHX从包被的OEC中的释放。通过测量4天后的抑制区域，测试了在第1天收集的洗出液的抗微生物活性，以针对变形链球菌和鼠李糖乳杆菌。通过扫描电子显微镜（SEM）观察OEC，以观察表面特征，比较：（1）未涂覆和涂覆的OEC以及（2）CHX释放前后。在28天内测量了OEC的力衰减。SEM分析表明OEC被纳米颗粒包覆。涂有CHX-HMP-5和CHX-HMP-1的OEC在28天内释放出CHX。涂层O ...