The stable nitroxide radical TEMPO [(2,2,6,6-Tetramethylpiperidin-1-yl)oxyl] has a multitude of applications in fields ranging from energy storage to biomedical applications and many more. However, to date, the processes of incorporating nitroxide radicals into thin-film coatings are laborious and not cost-effective, which hinders their wider use in many applications. In contrast, the authors have recently demonstrated the facile method of plasma polymerization of TEMPO into thin-film coatings that retain the stable nitroxide radicals. In this work, we are using three types of mass spectroscopic methods (plasma-mass spectrometry, time of flight secondary ion mass spectrometry, and high-performance liquid chromatography-mass spectrometry) and electron spin resonance to track the fate of the TEMPO molecule from monomer flask through the plasma and inside the resulting coatings. The results of this study demonstrate that TEMPO is a versatile monomer that can be used across different plasma reactors and reliably retain the stable nitroxide radical in the resulting thin-film coatings if certain process conditions are observed, namely, higher process pressures and lower powers.

中文翻译：

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成为激进者还是不成为一体？稳定的硝酸根自由基TEMPO [（2,2,6,6-四甲基哌啶-1-基）氧基]的命运正在等离子体聚合成薄膜涂层。

稳定的硝基自由基TEMPO [（2,2,6,6-四甲基哌啶-1-基）氧基]在从能量存储到生物医学的应用领域中有许多应用。然而，迄今为止，将氮氧化物自由基掺入薄膜涂层中的方法费力且不具有成本效益，这阻碍了其在许多应用中的广泛使用。相比之下，作者最近证明了将TEMPO等离子体聚合为保留稳定的氮氧自由基的薄膜涂层的简便方法。在这项工作中，我们使用三种类型的质谱方法（等离子质谱，飞行时间二次离子质谱，和高效液相色谱-质谱联用）和电子自旋共振，以跟踪TEMPO分子从单体瓶到血浆以及所得涂层内部的命运。这项研究的结果表明，TEMPO是一种通用单体，可在不同的等离子体反应器中使用，并且如果观察到某些工艺条件（即更高的工艺压力和更低的功率），则可以在生成的薄膜涂层中可靠地保留稳定的氮氧自由基。