Abstract

A hypocaloric diet, based on Orthodox fasting (OF) was followed by 29 overweight adults. A low-calorie, 16/8, time restricted eating (TRE) pattern was followed by 16 age- and weight-matched participants. Anthropometric, lipid, glycaemic and inflammation markers were assessed at baseline, at the end of the intervention (7 weeks from baseline) and 6 weeks after the cessation of diets (13 weeks from baseline). There was a trend of weight loss in both groups, which was evident at week 7 (TRE: −2.1 ± 1.0; OF: −2.0 ± 0.5 kg, p < 0.001 from baseline) and remained significant at week 13 (TRE: −2.9 ± 0.7; OF: −2.6 ± 0.3 kg, p < 0.001 from baseline). In the OF group, lipid concentrations declined at week 7 compared with baseline, increasing at week 13 compared with week 7. Our findings suggest that OF promotes a decrease in lipid concentrations, which however, is not evident 6 weeks after its end.

摘要

29 名超重成年人遵循基于正统禁食 (OF) 的低热量饮食。16 名年龄和体重匹配的参与者遵循低热量、16/8、限时饮食 (TRE) 模式。在基线、干预结束时（距基线 7 周）和停止饮食后 6 周（距基线 13 周）评估人体测量学、脂质、血糖和炎症标志物。两组都有体重减轻的趋势，这在第 7 周很明显（TRE：-2.1 ± 1.0；OF：-2.0 ± 0.5 kg， 与基线相比p < 0.001）并在第 13 周保持显着（TRE：-2.9 ± 0.7；OF：-2.6 ± 0.3 kg，p < 0.001 从基线）。在 OF 组中，与基线相比，第 7 周的脂质浓度下降，第 13 周与第 7 周相比有所增加。我们的研究结果表明，OF 促进了脂质浓度的降低，然而，这在其结束 6 周后并不明显。