Introduction

The national and international guidelines recommend evaluating all healthcare workers (HCWs) for their measles immune status and possibly vaccinating those who are seronegative.

Areas covered

We conducted a systematic review and meta-analysis in order to estimate the rate of measles susceptibility among HCWs in Italy and to explore possible options for the management of those found to be susceptible. Twenty-three studies were included in the meta-analysis. The prevalence of HCWs susceptible to measles was 11.5% (95%CI = 8.1–15.4%) and was higher in studies in which prevalence was evaluated by survey (16.7%; 95%CI = 8.9–26.3) than by the direct evaluation of blood specimens (9.1%; 95%CI = 6.2–12.5%). Occupational medicine examinations for measles screening with possible subsequent vaccination of seronegatives and the exclusion of susceptible HCWs from high-risk settings were common management strategies.

Expert opinion

HCWs susceptible to measles are an important epidemiological concern in Italy, and efforts to identify and actively offer the vaccine to this population should be increased.

中文翻译：

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意大利医护人员的麻疹易感性患病率和管理：系统评价和荟萃分析。

介绍

国家和国际准则建议对所有医护人员（HCW）的麻疹免疫状况进行评估，并可能为血清阴性的人接种疫苗。

覆盖区域

我们进行了系统的审查和荟萃分析，以估计意大利医护人员中麻疹易感性的比率，并探讨对易感人群进行管理的可能选择。荟萃分析包括23项研究。易感麻疹的HCW患病率为11.5％（95％CI = 8.1-15.4％），在通过调查评估患病率的研究中（16.7％; 95％CI = 8.9-26.3）高于直接评估血液样本（9.1％； 95％CI = 6.2–12.5％）。常见的管理策略是对麻疹进行筛查的职业医学检查以及随后可能的血清阴性疫苗的接种，以及将易感染的HCW排除在高风险环境之外的常见管理策略。

专家意见

在意大利，易患麻疹的HCW是重要的流行病学问题，应加大努力为该人群识别和积极提供疫苗。