Heme peroxidases are widely used as biological recognition elements in electrochemical biosensors for hydrogen peroxide and phenolic compounds. Various nature-derived and fully synthetic heme peroxidase mimics have been designed and their potential for replacing the natural enzymes in biosensors has been investigated. The use of semiconducting materials as transducers can thereby offer new opportunities with respect to catalyst immobilization, reaction stimulation, or read-out. This review focuses on approaches for the construction of electrochemical biosensors employing natural heme peroxidases as well as various mimics immobilized on semiconducting electrode surfaces. It will outline important advances made so far as well as the novel applications resulting thereof.

中文翻译：

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在半导体上使用天然和人造血红素过氧化物酶的电化学生物传感器。

血红素过氧化物酶被广泛用作过氧化氢和酚类化合物的电化学生物传感器中的生物识别元件。已经设计了各种天然来源的和完全合成的血红素过氧化物酶模拟物，并且已经研究了它们替代生物传感器中天然酶的潜力。因此，将半导体材料用作换能器可以提供关于催化剂固定，反应刺激或读出的新机会。这篇综述着重于构建利用天然血红素过氧化物酶以及固定在半导体电极表面上的各种模拟物的电化学生物传感器的方法。它将概述迄今为止取得的重要进展以及由此产生的新颖应用。