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Palladium‐Catalyzed One‐Pot Coupling / Cyclization through Mo(CO)6 as the Carbon Monoxide Donor: Synthesis of Quinazolinones
ChemistrySelect ( IF 2.1 ) Pub Date : 2020-07-01 , DOI: 10.1002/slct.202002111
Shou‐Wei Tao 1 , Rui‐Qing Liu 1 , Jing‐Ya Zhou 1 , Yong‐Ming Zhu 1
Affiliation  

An efficient and rapid one‐pot synthesis of quinazolinone via a three‐component carbonylative coupling of 2‐aminobenzamide or 2‐aminobenzonitrile, Mo(CO)6 and aryl bromides has been developed recently. This method provide a new way to synthesize quinazolinone which has a wide substrate scope, good functional group tolerance and mild reaction condition.

中文翻译:

钯催化一锅耦合/环化通过Mo(CO)6作为一氧化碳供体:喹唑啉酮的合成

最近开发了一种通过2-氨基苯甲酰胺或2-氨基苄腈,Mo(CO)6和芳基溴化物的三组分羰基化偶合反应快速高效地一锅合成喹唑啉酮的方法。该方法为底物范围广,官能团耐受性好,反应条件温和的喹唑啉酮的合成提供了新途径。
更新日期:2020-07-01
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