The Molecular Basis for Purine Binding Selectivity in the Bacterial ATP Synthase ϵ Subunit.,ChemBioChem

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The Molecular Basis for Purine Binding Selectivity in the Bacterial ATP Synthase ϵ Subunit.
ChemBioChem ( IF 2.6 ) Pub Date : 2020-06-30 , DOI: 10.1002/cbic.202000291
Alexander Krah _{1,

2} , Roland G Huber ₁ , Duncan G G McMillan ₃ , Peter J Bond _{1,

4}

Affiliation

The ups and downs of purine binding: Nucleotide binding to the bacterial ϵ subunit causes a conformational change from the up‐ to the down‐state. In this study, we clarify the structural and energetic basis of purine binding and the purine selectivity of the ϵ subunit from Bacillus PS3.