The Hill equation, which models the cooperative ligand‐receptor binding equilibrium, turns out to be useful in modeling the progression of infectious disease outbreaks such as CoViD‐19. The equation fits well the data for total and daily case numbers, allows tentative predictions for the half‐point and end point of the epidemic, and presents a mathematical characterization of how social interventions “flatten the curve” of the disease progression.

中文翻译：

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CoViD ‐19 流行遵循具有协同底物结合的酶的“动力学”

模拟配体-受体结合平衡的 Hill 方程被证明可用于模拟传染病爆发的进程，例如 CoViD-19。该方程很好地拟合了总病例数和每日病例数的数据，允许对流行的半点和终点进行初步预测，并提出了社会干预如何“拉平疾病进展曲线”的数学特征。