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Recent progress on electrochemical biosensing of aflatoxins: A review
Trends in Analytical Chemistry ( IF 11.8 ) Pub Date : 2020-07-01 , DOI: 10.1016/j.trac.2020.115966
Dong Liu , Wenjia Li , Chengxi Zhu , Yuye Li , Xiuli Shen , Libo Li , Xiaohong Yan , Tianyan You

Aflatoxin contamination causes tremendous economic losses and seriously threatens human health due to its prevalence in agricultural products and foods coupled with the severe toxicity of aflatoxins. Thus, sensitive, reliable, and rapid methods for aflatoxin analysis are urgently required. In recent years, electrochemical biosensors have emerged as a suitable alternative to gold standard methods that rely on sophisticated instruments (e.g. HPLC-MS). This review aims to describe recent advances (2016–2019) in electrochemical biosensors for aflatoxins detection in novel sensing strategies, recognition reporters, and integrated platforms. Particular emphasis is placed on the utilization of novel sensing strategies including dual-mode detection and ratiometric sensing in the fabrication of biosensors based on electrochemistry, photoelectrochemistry, and electrochemiluminescence. Meanwhile, a comprehensive discussion is provided on the challenges and perspectives related to electrochemical biosensing of aflatoxins.



中文翻译:

黄曲霉毒素电化学生物传感的最新研究进展

黄曲霉毒素的污染导致巨大的经济损失,并由于其在农产品和食品中的流行以及黄曲霉毒素的严重毒性而严重威胁人类健康。因此,迫切需要灵敏,可靠,快速的黄曲霉毒素分析方法。近年来,电化学生物传感器已成为依靠复杂仪器(例如HPLC-MS)的金标准方法的合适替代品。这篇综述旨在描述在新型传感策略,识别报告基因和集成平台中用于黄曲霉毒素检测的电化学生物传感器的最新进展(2016-2019年)。在基于电化学,光电化学,生物化学的生物传感器的制造中,应特别强调利用新颖的传感策略,包括双模式检测和比率传感。和电化学发光。同时,对与黄曲霉毒素电化学生物传感有关的挑战和观点进行了全面的讨论。

更新日期:2020-07-01
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