Abstract In the present work, an optimum set of microwave sintering parameters was used to fabricate a newly developed biomaterial, namely Mg3Zn1Ca15Nb, with improved mechanical and bio-corrosion properties. In the recent work by authors, sintering parameters were optimized using the conventional sintering route (R1) to sinter Mg3Zn1Ca15Nb, which resulted in improved mechanical and degradation properties. Subsequently, to achieve better properties of Mg3Zn1Ca15Nb over R1, a microwave sintering route (R2) was used to sinter the same material at similar parameters, which were used in R1. However, the obtained properties of magnesium alloy matrix composite (MgMCs) sintered using R2 were found to be lower than the R1. This article was aimed to optimize the sintering parameters by microwave sintering route (R3) to get significant results over R1. Sintering parameters such as heating rate, sintering temperature, and holding time were taken for optimization. Also, the influence of sintering parameters on the mechanical and bio-corrosion properties of MgMCs was studied. Experimentations were proceeded according to central composite design (CCD). The mechanical and bio-corrosion properties of Mg3Zn1Ca15Nb, sintered using R3 was better than the R2. However, these properties were still behind the properties of the sample sintered using R1. Scanning electron microscopy (SEM) images of the sample showed clustering of powders and micro-cracks on the surface of the sample sintered using R2. However, by increasing the heating rate, a reduction in powder clustering and micro-cracks were observed. Additionally, the microscopic image showed a reduction in the size of porosity with an increase in heating rate. No phase formation was observed in the microwave sintered samples as per X-ray diffraction (XRD) analysis. In addition to this, the hydrophilic nature of Mg3Zn1Ca15Nb showed a good agreement for cell adhesion. Subsequently, the bio-corrosion behaviour of fabricated samples was tested in simulated body fluid (SBF) containing pH 7.4 at 37 ± 0.5 °C. The obtained corrosion rate of sample sintered using R3 was less than R2, whereas it was still higher than R1.

中文翻译：

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使用微波烧结制备的 Mg3Zn1Ca15Nb 的力学性能和生物腐蚀行为的统计模型

摘要 在目前的工作中，一组最佳的微波烧结参数被用来制造一种新开发的生物材料，即 Mg3Zn1Ca15Nb，具有改进的机械和生物腐蚀性能。在作者最近的工作中，使用传统的烧结路线 (R1) 对烧结参数进行了优化，以烧结 Mg3Zn1Ca15Nb，从而提高了机械性能和降解性能。随后，为了获得比 R1 更好的 Mg3Zn1Ca15Nb 性能，使用微波烧结路线 (R2) 以类似的参数烧结 R1 中使用的相同材料。然而，发现使用 R2 烧结的镁合金基复合材料 (MgMCs) 的性能低于 R1。本文旨在通过微波烧结路线（R3）优化烧结参数，以获得优于R1的显着效果。对烧结参数如加热速率、烧结温度和保温时间进行优化。此外，还研究了烧结参数对 MgMCs 的机械和生物腐蚀性能的影响。根据中心复合设计（CCD）进行实验。使用 R3 烧结的 Mg3Zn1Ca15Nb 的机械和生物腐蚀性能优于 R2。然而，这些性能仍然落后于使用 R1 烧结的样品的性能。样品的扫描电子显微镜 (SEM) 图像显示使用 R2 烧结的样品表面有粉末聚集和微裂纹。然而，通过增加加热速率，观察到粉末聚集和微裂纹的减少。此外，显微图像显示孔隙尺寸随着加热速率的增加而减小。根据 X 射线衍射 (XRD) 分析，在微波烧结样品中没有观察到相形成。除此之外，Mg3Zn1Ca15Nb 的亲水性显示出良好的细胞粘附一致性。随后，在 37 ± 0.5 °C 下，在含有 pH 7.4 的模拟体液 (SBF) 中测试了制造样品的生物腐蚀行为。使用 R3 烧结的样品获得的腐蚀速率小于 R2，但仍高于 R1。在 37 ± 0.5 °C 下，在含有 pH 7.4 的模拟体液 (SBF) 中测试制造样品的生物腐蚀行为。使用 R3 烧结的样品获得的腐蚀速率小于 R2，但仍高于 R1。在 37 ± 0.5 °C 下，在含有 pH 7.4 的模拟体液 (SBF) 中测试制造样品的生物腐蚀行为。使用 R3 烧结的样品获得的腐蚀速率小于 R2，但仍高于 R1。