The conopeptides are the conotoxin of Conus loroisii have wide applications in drug development. This work emphasizes the isolation and identification of conopeptides form Conus loroisii and the peptides were characterized using LC–MS/MS ESI fragmentation technique and showing 50 protein sequences with disulfide linkages of the molecular mass of 352–1263 m/z. The conotoxin peptide having O1, O2, M, S, I1, J, A and T-superfamily. The gel electrophoresis results also confirmed the protein bands above 20 kDa. The Fourier transform infrared (FT-IR) spectra reported the presence of halometabolites found in marine-derived conopeptides. Moreover, the toxicity of conopeptide has been studied with brine shrimps, chorioallantoic membrane, and breast cancer cell lines (MCF-7). The in-silico analysis of HPV protein databases reveals conotoxin protein has strong interactions and the toxicity assay proved that the conotoxin of C. loroisii as a potential anti-cancer drug.

乳清蛋白的芋螺毒素是在药物开发中具有广泛的应用。这项工作着重于路氏锥虫中的肽段的分离和鉴定并使用LC–MS / MS ESI片段化技术对肽进行了表征，显示了具有二硫键的50个蛋白质序列，分子量为352–1263 m / z。具有O1，O2，M，S，I1，J，A和T超家族的芋螺毒素肽。凝胶电泳结果也证实了高于20kDa的蛋白条带。傅里叶变换红外（FT-IR）光谱报告了在海洋衍生的对映体肽中发现的卤代代谢物的存在。此外，已经用盐水虾，绒膜尿囊膜和乳腺癌细胞系（MCF-7）研究了conopepteptide的毒性。HPV蛋白质数据库的计算机模拟分析显示，芋螺毒素蛋白具有很强的相互作用，毒性实验证明罗氏梭状芽孢杆菌毒素是一种潜在的抗癌药物。