Nanomaterial synthesis, an enabler of amyloidosis inhibition against human diseases.,Nanoscale

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Nanomaterial synthesis, an enabler of amyloidosis inhibition against human diseases.
Nanoscale ( IF 5.8 ) Pub Date : 2020-06-30 , DOI: 10.1039/d0nr04273k
Nicholas Andrikopoulos ₁ , Yuhuan Li ₂ , Luca Cecchetto ₃ , Aparna Nandakumar ₁ , Tatiana Da Ros ₄ , Thomas P Davis ₅ , Kelly Velonia ₆ , Pu Chun Ke ₂

Affiliation

ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia.
Zhongshan Hospital, Fudan University, 111 Yixueyuan Rd, Xuhui District, Shanghai, China and ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia.
ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia. and Department of Chemical and Pharmaceutical Science, University of Trieste, Via Licio Giorgieri 1, 34127 Trieste, Italy.
Department of Chemical and Pharmaceutical Science, University of Trieste, Via Licio Giorgieri 1, 34127 Trieste, Italy.
ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia. and Australian Institute for Bioengineering and Nanotechnology, University of Queensland, Brisbane Qld 4072, Australia.
Department of Materials Science and Technology, University of Crete, Heraklion 70013, Greece.

Amyloid diseases are global epidemics with no cure currently available. In the past decade, the use of engineered nanomaterials as inhibitors or probes against the pathogenic aggregation of amyloid peptides and proteins has emerged as a new frontier in nanomedicine. In this Minireview, we summarize for the first time the pivotal role of chemical synthesis in enabling the development of this multidisciplinary field.

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